⛳ Invasive Carcinoma Of No Special Type

1 INTRODUCTION. Invasive breast carcinoma of no special type with medullary pattern (BCNST-MP) is a rare breast tumor that accounts for

Outcome: Most but not all of the published series recognize SRC to be more aggressive than mucinous carcinoma, invasive ductal carcinoma of no special type, and classic invasive lobular carcinoma of the breast, with frequent metastasis to regional lymph nodes and distant metastasis to the lung, liver, and bone but also with unusual sites of

(a–f) Invasive carcinoma of no special type (NST): Invasive carcinoma of no special type (NST) is the most common variety of breast carcinoma. It shows tumour cells arranged in acini, tubules (a, b↑→), clusters and trabeculae (a–d). The terminology for the most common type of breast cancer has changed from invasive ductal carcinoma, not otherwise specified (NOS) (2003) to invasive carcinoma of no special type (NST) (2012). This group of breast cancers comprises all tumors without the specific differentiating features that characterize the other categories of breast cancers. ^{Invasive lobular carcinoma is the most common special breast carcinoma subtype, with unique morphological (discohesive cells, single-cell files, targetoid pattern) and immunohistochemical (loss of E-cadherin and β-catenin staining) features. Moreover, ILC displays a poor response to neoadjuvant therapy, a different metastatic pattern compared to invasive breast carcinoma of no special type}

IDC NST is defined by the 2012 World Health Organization (WHO) classification as “the heterogeneous group of tumors that fail to exhibit sufficient characteristics to achieve classification as a specific histological type.”There are 21 special subtypes of invasive breast cancer. Invasive lobular carcinoma (ILC) is the most common (5–15%

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